When your large cat has a sensitive stomach, the last thing you want is a carrier that adds stress or makes cleanup a nightmare. Our team evaluated five popular soft-sided carriers designed for cats over 15 pounds, focusing on features that matter for digestive health: smooth, wipeable interiors, superior airflow, and sturdy construction that minimizes motion sickness. We cross-referenced manufacturer specs with hundreds of owner reviews to see which models hold up to repeated use and accidents. In our evaluation, we looked for carriers with waterproof bases, mesh panels for ventilation, and easy-access openings for quick cleaning. We also prioritized comfort features like padded floors and shoulder straps that make it easier to transport a heavy cat without jostling. Below are our picks, chosen for their ability to keep both you and your sensitive-stomached cat calm and clean on the go.

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